Journal article

The direct formation of glycosyl thiols from reducing sugars allows one-pot protein glycoconjugation.

Abstract:: (Figure Presented) Sweet and easy: A one-pot method consisting of direct thionation (1) followed by thiol-mediated chemoselective ligation (2) can be used for site-selective protein glycosylation. This procedure, which uses the Lawesson reagent, has been shown to be fully compatible with unprotected sugars, the products of which can be directly used in a selenenylsulfide protein glycosylation strategy. © 2006 Wiley-VCH Verlag GmbH and Co. KGaA.

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Bernardes, G., Gamblin, D., & Davis, B. (2006). The direct formation of glycosyl thiols from reducing sugars allows one-pot protein glycoconjugation. Angewandte Chemie (International Ed. in English), 45(24), 4007–4011.

MLA Style

Bernardes, G, et al. “The Direct Formation of Glycosyl Thiols from Reducing Sugars Allows One-Pot Protein Glycoconjugation.” Angewandte Chemie (International Ed. in English), vol. 45, no. 24, 2006, pp. 4007–11.

Chicago Style

Bernardes, G, D Gamblin, and B Davis. 2006. “The Direct Formation of Glycosyl Thiols from Reducing Sugars Allows One-Pot Protein Glycoconjugation.” Angewandte Chemie (International Ed. in English) 45 (24): 4007–11.
Print

Access Document

Publisher copy:: 10.1002/anie.200600685

Authors

+ Bernardes, G More by this author

Role:: Author

+ Gamblin, D More by this author

Role:: Author

+ Davis, B More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: Angewandte Chemie (International ed. in English) More from this journal
Volume:: 45
Issue:: 24
Pages:: 4007-4011
Publication date:: 2006-06-01
DOI:: 10.1002/anie.200600685
EISSN:: 1521-3773
ISSN:: 1433-7851

Language:: English
Keywords:: Dioxanes

Glycosylation

Organothiophosphorus Compounds

Sulfhydryl Compounds

Subtilisin

Carbohydrates
Pubs id:: pubs:33462
UUID:: uuid:5b5d813e-d773-4fc4-85b9-12fdf7e89e97
Local pid:: pubs:33462
Source identifiers:: 33462
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_5b5d813ed7734fc485b912fdf7e89e97

Terms of use

Copyright date:: 2006

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP