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Reversible photo-control over transmembrane anion transport using visible-light responsive supramolecular carriers

Abstract:
Ion transport across lipid bilayer membranes in biology is controlled by membrane proteins, which in turn are regulated in response to chemical-, physical- and photo-stimuli. The design of synthetic supramolecular ion transporters able to be precisely controlled by external signals, in particular bio-compatible wavelengths of visible light, is key for achieving spatio-temporal control over function. Here we report two-colour responsive molecular photo-switches that act as supramolecular transmembrane anion carriers. Reversible switching of the photo-switch within the lipid bilayer membrane is achieved using biocompatible visible wavelengths of light, such that temporal control over transmembrane anion transport is achieved through alternating irradiation with red and blue light.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/d0sc02745f

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
ORCID:
0000-0003-1555-3479


Publisher:
Royal Society of Chemistry
Journal:
Chemical Science More from this journal
Volume:
11
Issue:
24
Pages:
6325-6331
Publication date:
2020-06-04
Acceptance date:
2020-06-04
DOI:
EISSN:
2041-6539
ISSN:
2041-6520


Language:
English
Keywords:
Pubs id:
1109136
Local pid:
pubs:1109136
Deposit date:
2020-06-04

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