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Subventricular zone cell migration: lessons from quantitative two-photon microscopy.

Abstract:

Neuroblasts born in the adult subventricular zone (SVZ) migrate long distances in the rostral migratory stream (RMS) to the olfactory bulbs where they integrate into circuitry as functional interneurons. As very little was known about the dynamic parameters of SVZ neuroblast migration, we used two-photon time-lapse microscopy to analyze migration in acute slices. This involved analyzing 3D stacks of images over time and uncovered several novel aspects of SVZ migration: chains remain stable, c...

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Publisher copy:
10.3389/fnins.2011.00030

Authors


Hockberger, PE More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Frontiers in neuroscience
Volume:
5
Issue:
MAR
Pages:
30
Publication date:
2011
DOI:
EISSN:
1662-453X
ISSN:
1662-4548
URN:
uuid:5b0f6977-326f-4bf1-8c3c-3b6d48a91e13
Source identifiers:
131252
Local pid:
pubs:131252

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