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Heterogeneous properties of central lateral and parafascicular thalamic synapses in the striatum.

Abstract:

To understand the principles of operation of the striatum it is critical to elucidate the properties of the main excitatory inputs from cortex and thalamus, as well as their ability to activate the main neurons of the striatum, the medium spiny neurons (MSNs). As the thalamostriatal projection is heterogeneous, we set out to isolate and study the thalamic afferent inputs to MSNs using small localized injections of adeno-associated virus carrying fusion genes for channelrhodopsin-2 and YFP, in...

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Publication status:
Published

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Authors


Ellender, TJ More by this author
Harwood, J More by this author
Kosillo, P More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
More by this author
Institution:
University of Oxford
Department:
Oxford
Journal:
The Journal of physiology
Volume:
591
Issue:
Pt 1
Pages:
257-272
Publication date:
2013-01-05
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
URN:
uuid:5af192b7-4e7f-4564-84e0-6178dc12e0a7
Source identifiers:
358606
Local pid:
pubs:358606

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