- Abstract:
-
There are limited data on the pharmacokinetic and safety profiles of artesunate-amodiaquine in human immnunodeficiency virus infected (HIV+) individuals receiving antiretroviral therapy. In a two-step intensive sampling pharmacokinetic trial, we compared area under the concentration-time curve from 0 to 28 days (AUC0-28 days) of an active metabolite of amodiaquine, desethylamodiaquine, and treatment-emergent adverse events between antiretroviral therapy-naive HIV+ adults and those taking nevi...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 517.7kb)
-
- Publisher copy:
- 10.1128/aac.00412-18
-
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- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Antimicrobial Agents and Chemotherapy Journal website
- Volume:
- 62
- Issue:
- 7
- Pages:
- e00412-18
- Publication date:
- 2018-05-14
- Acceptance date:
- 2018-05-14
- DOI:
- EISSN:
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1098-6596
- ISSN:
-
0066-4804
- Pubs id:
-
pubs:848004
- URN:
-
uri:5a85901f-8213-49e2-9be6-0e6b01520a78
- UUID:
-
uuid:5a85901f-8213-49e2-9be6-0e6b01520a78
- Local pid:
- pubs:848004
- Language:
- English
- Keywords:
- Copyright holder:
- Banda et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Banda et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Journal article
Pharmacokinetics and safety profile of artesunate-amodiaquine co-administered with antiretroviral therapy in malaria uninfected HIV-positive Malawian adults
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