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Spatial and spatio-temporal methods for mapping malaria risk: a systematic review

Abstract:
BACKGROUND:
Approaches in malaria risk mapping continue to advance in scope with the advent of geostatistical techniques spanning both the spatial and temporal domains. A substantive review of the merits of the methods and covariates used to map malaria risk has not been undertaken. Therefore, this review aimed to systematically retrieve, summarise methods and examine covariates that have been used for mapping malaria risk in sub-Saharan Africa (SSA).
METHODS:
A systematic search of malaria risk mapping studies was conducted using PubMed, EBSCOhost, Web of Science and Scopus databases. The search was restricted to refereed studies published in English from January 1968 to April 2020. To ensure completeness, a manual search through the reference lists of selected studies was also undertaken. Two independent reviewers completed each of the review phases namely: identification of relevant studies based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, data extraction and methodological quality assessment using a validated scoring criterion.
RESULTS:
One hundred and seven studies met the inclusion criteria. The median quality score across studies was 12/16 (range: 7-16). Approximately half (44%) of the studies employed variable selection techniques prior to mapping with rainfall and temperature selected in over 50% of the studies. Malaria incidence (47%) and prevalence (35%) were the most commonly mapped outcomes, with Bayesian geostatistical models often (31%) the preferred approach to risk mapping. Additionally, 29% of the studies employed various spatial clustering methods to explore the geographical variation of malaria patterns, with Kulldorf scan statistic being the most common. Model validation was specified in 53 (50%) studies, with partitioning data into training and validation sets being the common approach.
CONCLUSIONS:
Our review highlights the methodological diversity prominent in malaria risk mapping across SSA. To ensure reproducibility and quality science, best practices and transparent approaches should be adopted when selecting the statistical framework and covariates for malaria risk mapping. Findings underscore the need to periodically assess methods and covariates used in malaria risk mapping; to accommodate changes in data availability, data quality and innovation in statistical methodology.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmjgh-2020-002919

Authors


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Role:
Author
ORCID:
0000-0002-9817-1849
More by this author
Role:
Author
ORCID:
0000-0003-3410-1881
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0003-3725-6088


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Grant:
103602/Z/14/Z
212176/Z/18/Z


Publisher:
BMJ Publishing Group
Journal:
BMJ Global Health More from this journal
Volume:
5
Issue:
10
Article number:
e002919
Publication date:
2020-10-01
Acceptance date:
2020-08-24
DOI:
EISSN:
2059-7908
ISSN:
2059-7908
Pmid:
33023880


Language:
English
Keywords:
Pubs id:
1136805
Local pid:
pubs:1136805
Deposit date:
2020-10-30

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