- Abstract:
-
It is well established that the intracellular accumulation of Aβ (amyloid β-peptide) is associated with AD (Alzheimer's disease) and that this accumulation is toxic to neurons. The precise mechanism by which this toxicity occurs is not well understood; however, identifying the causes of this toxicity is an essential step towards developing treatments for AD. One intracellular location where the accumulation of Aβ can have a major effect is within mitochondria, where mitochondrial proteins hav...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1042/bst0390868
-
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- Journal:
- Biochemical Society transactions
- Volume:
- 39
- Issue:
- 4
- Pages:
- 868-873
- Publication date:
- 2011-08-05
- DOI:
- EISSN:
-
1470-8752
- ISSN:
-
0300-5127
- URN:
-
uuid:5a544b3e-c1d1-4791-bc97-df079010eab0
- Source identifiers:
-
167535
- Local pid:
- pubs:167535
- Copyright date:
- 2011
Journal article
Mitochondrial β-amyloid in Alzheimer's disease.
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