Discrimination, reversal, and shift learning in Huntington's disease: mechanisms of impaired response selection.
In a series of three experiments, we investigated different aspects of response selection in early-stage clinically symptomatic Huntington's disease (HD) patients in the context of discrimination learning. A series of structurally related response selection tasks involving discrimination, reversal, and shift learning were employed. In Experiment 1, the mechanisms of our previously reported  finding of impaired extra-dimensional shift learning were explored. The results suggested that impa...Expand abstract
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