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Boundary spike-layer solutions of the singular Keller-Segel system: existence, profiles and stability

Abstract:

This paper investigates boundary-layer solutions of the singular Keller-Segel system (proposed in [19]) in multi-dimensional domains, which describes cells’ chemotactic movement toward the concentration gradient of the nutrient they consume, subject to a zero-flux boundary condition for the cell density and a Dirichlet boundary condition for the nutrient. The steady-state problem of the system reduces to a scalar nonlocal Dirichlet elliptic problem with a singularity. By analyzing this nonlocal problem, we establish the existence of a unique steady-state solution which forms a boundary spike-layer profile as the nutrient diffusion coefficient ε → 0. For radially symmetric domains, we derive explicit expansions for the boundary-layer steepness and thickness in terms of the domain radius (for small ε > 0), which quantifies the influence of radius on the profile and thickness. Additionally, we prove the nonlinear exponential stability of this boundary-layer steady-state in radially symmetric domains. The key challenge in our analysis is the emergence of a singularity for small ε in both stationary and time-dependent problems. To address this, we reduce the nonlocal steady-state problem to a local one and conduct a refined analysis via the barrier method and Fermi coordinates, yielding sharp estimates for the local steady-state solution near the boundary. This approach enables us to determine the asymptotic profile of the nonlocal problem’s solution as ε → 0, accurately capturing and properly resolving the singularity to establish our main results. For the time-dependent problem in radially symmetric domains, we employ a variable transformation to eliminate the singularity, ultimately proving the nonlinear stability of the unique steady-state solution. Our analysis leverages the equation governing the radial mass distribution function relative to the steady state, along with delicate time-weighted energy estimates.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1112/plms.70122

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author


Publisher:
Wiley
Journal:
Proceedings of the London Mathematical Society More from this journal
Volume:
132
Issue:
2
Article number:
e70122
Publication date:
2026-02-11
Acceptance date:
2025-12-25
DOI:
EISSN:
1460-244X
ISSN:
0024-6115


Language:
English
Keywords:
Pubs id:
2042666
Local pid:
pubs:2042666
Deposit date:
2025-12-25
ARK identifier:

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