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The Kalash Genetic Isolate? The evidence for recent admixture

Abstract:
The recent paper “The Kalash Genetic Isolate: Ancient Divergence, Drift, and Selection”, by Ayub et al1 (AJHG 2015, 96:1-9) suggests that the Kalash people of present-day Pakistan experienced “no detectable gene flow from their geographic neighbors in Pakistan or from other extant Eurasian populations” since their split from those populations over 8000 years ago. They note that this finding of apparent genetic isolation contradicts the results of Hellenthal et al2, who inferred DNA introgression dated to 910-220BCE in an overlapping sample of Kalash individuals. Hellenthal et al2 inferred the (unknown) source of this DNA to have genetic similarities to a wide range of modern-day groups from West Asia and Europe, including Germany-Austria and Turkey, for example.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ajhg.2015.12.025

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author


Publisher:
Elsevier
Journal:
American Journal of Human Genetics More from this journal
Volume:
98
Issue:
2
Pages:
396-397
Publication date:
2016-02-04
Acceptance date:
2015-12-30
DOI:
EISSN:
1537-6605
ISSN:
0002-9297


Language:
English
Pubs id:
pubs:601359
UUID:
uuid:59b88a68-f6fe-4e8d-a338-646cac720c6f
Local pid:
pubs:601359
Source identifiers:
601359
Deposit date:
2016-02-15

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