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Journal article

Novel ketone diet enhances physical and cognitive performance

Abstract:

Ketone bodies are the most energy-efficient fuel and yield more ATP per mole of substrate than pyruvate and increase the free energy released from ATP hydrolysis. Elevation of circulating ketonesviahigh-fat, lowcarbohydrate diets has been used for the treatment of drug-refractory epilepsy and for neurodegenerative diseases, such as Parkinson’s disease. Ketones may also be beneficial for muscle and brain in times of stress, such as endurance exercise. The challenge has been to raise circula...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1096/fj.201600773R

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Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Author
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Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Department:
Oxford, MSD, Biochemistry
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Funding agency for:
Murray, AJ
Defense Advanced Research Projects Agency More from this funder
Publisher:
Federation of American Societies for Experimental Biology Publisher's website
Journal:
The FASEB Journal Journal website
Publication date:
2016-08-05
Acceptance date:
2016-08-08
DOI:
ISSN:
1530-6860
Pubs id:
pubs:656072
URN:
uri:58ea8427-bb29-43fa-83f4-62ef132e1657
UUID:
uuid:58ea8427-bb29-43fa-83f4-62ef132e1657
Local pid:
pubs:656072

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