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Implant failure in bilateral metal-on-metal hip resurfacing arthroplasties: A clinical and pathological study

Abstract:

Metal-on-metal hip resurfacing arthroplasties (MoMHRAs) have a high failure rate due to pseudotumour formation. It is not certain whether pseudotumours in bilateral MoMHRAs form on the basis of an adverse reaction to metal debris (ARMD) that is entirely due to a local innate and adaptive immune response to Cobalt-Chrome (Co-Cr) wear particles. To determine if there is a systemic component to ARMD in bilateral MoMHRAs, we examined the histology of ARMD in unilateral and bilateral MoMHRAs revis...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s10856-018-6037-5

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
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Publisher:
Springer Publisher's website
Journal:
Journal of Materials Science: Materials in Medicine Journal website
Volume:
29
Issue:
3
Pages:
28
Publication date:
2018-03-07
Acceptance date:
2018-02-22
DOI:
EISSN:
1573-4838
ISSN:
0957-4530
Pubs id:
pubs:828756
URN:
uri:58a58938-dba5-4b33-afba-1c8d6086460f
UUID:
uuid:58a58938-dba5-4b33-afba-1c8d6086460f
Local pid:
pubs:828756
Language:
English
Keywords:

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