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Feno and blood eosinophils as biomarkers in predicting asthma exacerbations

Abstract:
With advances in new therapies that target airway inflammation, there is an urgent need for accurate and easy-to-use biomarkers to predict asthma exacerbations and likely patient responses to treatment. Blood and sputum eosinophilia are used to predict the response of patients with asthma to steroid therapy. Similarly, fractional exhaled nitric oxide (FeNO) concentrations has been shown to predict response to antiinflammatory therapy. Efforts have been made to correlate FeNO and blood eosinophil counts as composite biomarkers but so far results have been inconsistent.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/thoraxjnl-2017-210983.340

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Oxford college:
St Edmund Hall
Role:
Author
ORCID:
0000-0002-4288-5973


Publisher:
BMJ Publishing Group
Host title:
British Thoracic Society Winter Meeting 2017
Journal:
British Thoracic Society Winter Meeting 2017 More from this journal
Publication date:
2017-11-15
DOI:


Pubs id:
pubs:855780
UUID:
uuid:5899980a-dfdc-4c43-9ce2-fd3c8dcc7f8a
Local pid:
pubs:855780
Source identifiers:
855780
Deposit date:
2018-08-30
ARK identifier:

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