An economical regimen of human diploid cell strain anti-rabies vaccine for post-exposure prophylaxis.

Journal article

Vaccine regimens using 0.1 ml human diploid cell strain vaccine (HDCSV) given intradermally (id) in single and multiple sites, or with aluminum hydroxide adjuvant given subcutaneously (sc), were compared with the regimens of HDCSV and Semple vaccine currently suggested by WHO. Some groups were also given human rabies-immune globulin (HRIG). Neutralising antibody titres were monitored for 3 months. Antibody was detected earliest in subjects given 0.1 ml HDCSV id at each of eight sites. The hig...

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Authors: Warrell, M; Warrell, D; Suntharasamai, P; Viravan, C; Sinhaseni, A

• Publication status: Published
• Journal: Lancet
• Volume: 2
• Issue: 8345
• Pages: 301-304
• Publication date: 1983-08-01
• DOI: 10.1016/s0140-6736(83)90288-x
• EISSN: 1474-547X
• ISSN: 0140-6736
• Language: English
• Keywords: Adult; Injections, Intramuscular; Costs and Cost Analysis; Rabies virus; Random Allocation; Humans; Aged; Immunization, Secondary; Adolescent; Rabies Vaccines; Middle Aged; Vaccination; Rabies; Male; Clinical Trials as Topic; Injections, Intradermal; Injections, Subcutaneous; Antibodies, Viral; Female