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Human glandular kallikrein 2 levels in serum for discrimination of pathologically organ-confined from locally-advanced prostate cancer in total PSA-levels below 10 ng/ml.

Abstract:

BACKGROUND: We measured serum levels of human glandular kallikrein 2 (hK2) in patients treated with radical retropubic prostatectomy (rrP) for clinically localized prostate cancer (PCa) with a total PSA (tPSA)-level below 10 ng/ml to investigate whether hK2 can be applied to preoperatively distinguish organ-confined (pT2a/b) from nonorgan-confined (> or = pT3a)-PCa more accurately than total PSA. Further, we evaluated hK2, free- and tPSA-concentrations in all pathologic stages of PCa. METH...

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Publisher copy:
10.1002/pros.1123

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Journal:
The Prostate
Volume:
49
Issue:
2
Pages:
101-109
Publication date:
2001-10-05
DOI:
EISSN:
1097-0045
ISSN:
0270-4137
URN:
uuid:57fa32a7-a75f-4610-b9bf-ce92fd1b4092
Source identifiers:
366031
Local pid:
pubs:366031

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