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Journal article

Analysis of U1 small nuclear RNA interaction with cyclin H.

Abstract:

TFIIH is a general transcription and repair factor implicated in RNA polymerase II transcription, nucleotide excision repair, and transcription-coupled repair. Genetic defects in TFIIH lead to three distinct inheritable diseases: xeroderma pigmentosa, Cockayne syndrome, and trichothiodystrophy, with xeroderma pigmentosa patients being highly susceptible to skin cancer. Earlier data revealed that the cyclin H subunit of TFIIH associates with U1 small nuclear RNA, a core-splicing component. In ...

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Publication status:
Published

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Publisher copy:
10.1074/jbc.m505791200

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of biological chemistry
Volume:
280
Issue:
44
Pages:
36920-36925
Publication date:
2005-11-01
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
Source identifiers:
56066

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