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Characterization of G6PD genotypes and phenotypes on the northwestern

Abstract:

Mutations in the glucose-6-phosphate dehydrogenase (G6PD) gene result in red blood cells with increased susceptibility to oxidative damage. Significant haemolysis can be caused by primaquine and other 8-aminoquinoline antimalarials used for the radical treatment of Plasmodium vivax malaria. The distribution and phenotypes of mutations causing G6PD deficiency in the male population of migrants and refugees in a malaria endemic region on the Thailand-Myanmar border were characterized. Blood sam...

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Publisher copy:
10.1371/journal.pone

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Publisher:
Public Library of Science
Journal:
PLoS ONE
Volume:
9
Issue:
12
Publication date:
2014-12-23
DOI:
EISSN:
1932-6203
URN:
uuid:57775361-a602-4ebb-a8f1-b4b51d413041
Source identifiers:
502291
Local pid:
pubs:502291
Language:
English

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