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Journal article

Super-resolved traction force microscopy (STFM)

Abstract:
Measuring small forces is a major challenge in cell biology. Here we improve the spatial resolution and accuracy of force reconstruction of the well-established technique of traction force microscopy (TFM) using STED microscopy. The increased spatial resolution of STED-TFM (STFM) allows a greater than 5-fold higher sampling of the forces generated by the cell than conventional TFM, accessing the nano instead of the micron scale. This improvement is highlighted by computer simulations and an activating RBL cell model system.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1021/acs.nanolett.6b00273

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Publisher:
American Chemical Society Publisher's website
Journal:
Nano Letters Journal website
Volume:
16
Issue:
4
Pages:
2633-2638
Publication date:
2016-02-29
DOI:
EISSN:
1530-6992
ISSN:
1530-6984
URN:
uuid:576f5500-569f-4256-823a-5583b3a42fd5
Source identifiers:
609109
Local pid:
pubs:609109

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