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Journal article

Should methotrexate have any place in the treatment of psoriatic arthritis?

Abstract:
Methotrexate (MTX) is widely used in the treatment of psoriatic arthritis (PsA) despite the evidence base for this being limited. This narrative review summarises the evidence to date of using MTX within different domains of psoriatic disease, including peripheral arthritis, axial disease, dactylitis, enthesitis, psoriasis and nail disease. We also explore the role of MTX in combination therapy with tumour necrosis factor inhibitors, in addition to its safety and tolerability, to answer the question: should methotrexate have any place in the treatment of psoriatic arthritis?
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/j.rdc.2019.04.007

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-4756-663X


More from this funder
Funding agency for:
Coates, L
Grant:
Clinician Scientist award


Publisher:
Elsevier
Journal:
Rheumatic Disease Clinics of North America More from this journal
Volume:
45
Issue:
3
Pages:
325-339
Publication date:
2019-05-30
Acceptance date:
2019-04-24
DOI:
EISSN:
1558-3163
ISSN:
0889-857X


Language:
English
Keywords:
Pubs id:
pubs:1022723
UUID:
uuid:56ee317b-4e44-4820-bc00-23debc7b87c1
Local pid:
pubs:1022723
Source identifiers:
1022723
Deposit date:
2019-07-01

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