Journal article
RECONsidering sensing of cyclic dinucleotides
- Abstract:
- Detection of cyclic dinucleotides (cdNs) by the STING pathway potently triggers the antiviral response. McFarland et al. now show that the mouse oxidoreductase RECON acts as a sensor for some bacterial cdNs, modulating innate signaling in a manner independent of STING to promote an antibacterial state.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
-
(Preview, Accepted manuscript, pdf, 244.0KB, Terms of use)
-
- Publisher copy:
- 10.1016/j.immuni.2017.03.005
Authors
- Publisher:
- Cell Press
- Journal:
- Immunity More from this journal
- Volume:
- 46
- Issue:
- 3
- Pages:
- 337-339
- Publication date:
- 2017-03-21
- Acceptance date:
- 2017-01-13
- DOI:
- EISSN:
-
1097-4180
- ISSN:
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1074-7613
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:686805
- UUID:
-
uuid:56d07d04-6c8e-46ef-a267-763f5538362d
- Local pid:
-
pubs:686805
- Source identifiers:
-
686805
- Deposit date:
-
2017-07-20
- ARK identifier:
Terms of use
- Copyright holder:
- Elsevier Inc
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Elsevier Inc. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.immuni.2017.03.005
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