Journal article icon

Journal article

RECONsidering sensing of cyclic dinucleotides

Abstract:
Detection of cyclic dinucleotides (cdNs) by the STING pathway potently triggers the antiviral response. McFarland et al. now show that the mouse oxidoreductase RECON acts as a sensor for some bacterial cdNs, modulating innate signaling in a manner independent of STING to promote an antibacterial state.
Publication status:
Published
Peer review status:
Peer reviewed

Actions

Access Document

Files:
Publisher copy:
10.1016/j.immuni.2017.03.005

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author


Publisher:
Cell Press
Journal:
Immunity More from this journal
Volume:
46
Issue:
3
Pages:
337-339
Publication date:
2017-03-21
Acceptance date:
2017-01-13
DOI:
EISSN:
1097-4180
ISSN:
1074-7613


Language:
English
Keywords:
Pubs id:
pubs:686805
UUID:
uuid:56d07d04-6c8e-46ef-a267-763f5538362d
Local pid:
pubs:686805
Source identifiers:
686805
Deposit date:
2017-07-20
ARK identifier:

Terms of use


Views and Downloads

Views and downloads will return soon






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP