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Impact of viral upper respiratory tract infection on the concentration of nasopharyngeal pneumococcal carriage among Kenyan children

Abstract:

Viral upper respiratory tract infection (URTI) predisposes to bacterial pneumonia possibly by facilitating growth of bacteria such as Streptococcus pneumoniae colonising the nasopharynx. We investigated whether viral URTI is temporally associated with an increase in nasopharyngeal pneumococcal concentration. Episodes of symptomatic RSV or rhinovirus URTI among children <5 years were identified from a longitudinal household study in rural Kenya. lytA and alu PCR were performed on nasopharyn...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/s41598-018-29119-w

Authors


Morpeth, SC More by this author
Munywoki, P More by this author
Hammitt, LL More by this author
Bottomley, C More by this author
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
8
Issue:
1
Pages:
11030
Publication date:
2018-07-23
Acceptance date:
2018-07-02
DOI:
EISSN:
2045-2322
ISSN:
2045-2322
Pubs id:
pubs:892110
URN:
uri:56ac8afe-5e2d-48ee-897c-cf418227df4d
UUID:
uuid:56ac8afe-5e2d-48ee-897c-cf418227df4d
Local pid:
pubs:892110
Keywords:

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