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Journal article

Recognition and catabolism of synthetic heterotrimeric collagen peptides by matrix metalloproteinases.

Abstract:

BACKGROUND: The general consensus is that interstitial collagens are digested by collagenases and denatured collagen by gelatinases, although processing of fibrillar and acetic-acid-soluble collagen by gelatinase A has also been reported. One of the main difficulties in studying the mechanism of action of these matrix metalloproteinases (MMPs) derives from the physicochemical properties of the natural triple-helical collagen, which makes it difficult to handle. RESULTS: Synthetic heterotrimer...

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Publication status:
Published

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Journal:
Chemistry and biology
Volume:
7
Issue:
2
Pages:
119-132
Publication date:
2000-02-01
DOI:
EISSN:
1879-1301
ISSN:
1074-5521
Source identifiers:
226735

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