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Magnetoencephalography recordings reveal the spatiotemporal dynamics of recognition memory for complex versus simple auditory sequences

Abstract:
Auditory recognition is a crucial cognitive process that relies on the organization of single elements over time. However, little is known about the spatiotemporal dynamics underlying the conscious recognition of auditory sequences varying in complexity. To study this, we asked 71 participants to learn and recognize simple tonal musical sequences and matched complex atonal sequences while their brain activity was recorded using magnetoencephalography (MEG). Results reveal qualitative changes in neural activity dependent on stimulus complexity: recognition of tonal sequences engages hippocampal and cingulate areas, whereas recognition of atonal sequences mainly activates the auditory processing network. Our findings reveal the involvement of a cortico-subcortical brain network for auditory recognition and support the idea that stimulus complexity qualitatively alters the neural pathways of recognition memory.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s42003-022-04217-8

Authors


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Role:
Author
ORCID:
0000-0003-4646-1315
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Role:
Author
ORCID:
0000-0003-0676-6464
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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
ORCID:
0000-0002-3908-6898


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Funder identifier:
https://ror.org/00znyv691
Grant:
DNRF117


Publisher:
Springer Nature
Journal:
Communications Biology More from this journal
Volume:
5
Issue:
1
Article number:
1272
Publication date:
2022-11-19
Acceptance date:
2022-11-02
DOI:
EISSN:
2399-3642
Pmid:
36402843


Language:
English
Keywords:
Pubs id:
1308668
Local pid:
pubs:1308668
Deposit date:
2024-10-03

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