ATP-sensitive K+ channels couple cell metabolism to electrical activity in nerve, muscle and endocrine cells, and play important roles in these tissues under both physiological and pathological conditions. The KATP channel is an octameric complex of two unrelated types of subunit: a pore-forming subunit (Kir6.2) and a regulatory subunit, the sulphonylurea receptor (SUR). This review focuses on the regulation of KATP channel activity by nucleotides and cell metabolism and considers which regul...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Correlating structure and function in ATP-sensitive K+ channels.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record