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Crystal structure of SANOS, a bacterial nitric oxide synthase oxygenase protein from Staphylococcus aureus.

Abstract:

Prokaryotic genes related to the oxygenase domain of mammalian nitric oxide synthases (NOSs) have recently been identified. Although they catalyze the same reaction as the eukaryotic NOS oxygenase domain, their biological function(s) are unknown. In order to explore rationally the biochemistry and evolution of the prokaryotic NOS family, we have determined the crystal structure of SANOS, from methicillin-resistant Staphylococcus aureus (MRSA), to 2.4 A. Haem and S-ethylisothiourea (SEITU) are...

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Publication status:
Published

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Journal:
Structure (London, England : 1993)
Volume:
10
Issue:
12
Pages:
1687-1696
Publication date:
2002-12-01
DOI:
EISSN:
1878-4186
ISSN:
0969-2126
Source identifiers:
72610
Language:
English
Keywords:
Pubs id:
pubs:72610
UUID:
uuid:55bdefda-6483-432c-83ee-8a584d31e63d
Local pid:
pubs:72610
Deposit date:
2012-12-19

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