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The impact of daily cotrimoxazole prophylaxis and antiretroviral therapy on mortality and hospital admissions in HIV-infected Zambian children.

Abstract:

BACKGROUND: Data on the population effectiveness of cotrimoxazole prophylaxis and antiretroviral therapy (ART) in human immunodeficiency virus (HIV)-infected African children are few. METHODS: A total of 534 Zambian children with HIV infection were randomized to receive daily cotrimoxazole prophylaxis or placebo in the Children with HIV Antibiotic Prophylaxis trial. Following trial closure, children who received the placebo initiated cotrimoxazole prophylaxis, and all children were observed i...

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Publication status:
Published

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Publisher copy:
10.1086/515396

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Mulenga, V More by this author
Kabamba, D More by this author
Sinyinza, F More by this author
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Journal:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume:
44
Issue:
10
Pages:
1361-1367
Publication date:
2007-05-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:55b8a681-c504-45fa-8a42-dd60bf3e641f
Source identifiers:
422643
Local pid:
pubs:422643

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