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Journal article

Prediction of brain age and cognitive age: quantifying brain and cognitive maintenance in aging

Abstract:

The concept of brain maintenance refers to the preservation of brain integrity in older age, while cognitive reserve refers to the capacity to maintain cognition in the presence of neurodegeneration or aging‐related brain changes. While both mechanisms are thought to contribute to individual differences in cognitive function among older adults, there is currently no “gold standard” for measuring these constructs. Using machine‐learning methods, we estimated brain and cognitive age based on de...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/hbm.25316

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
ORCID:
0000-0002-0540-9353
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Publisher:
Wiley Publisher's website
Journal:
Human Brain Mapping Journal website
Volume:
42
Issue:
6
Pages:
1626-1640
Publication date:
2020-12-14
Acceptance date:
2020-12-01
DOI:
EISSN:
1097-0193
ISSN:
1065-9471
Language:
English
Keywords:
Pubs id:
1147466
Local pid:
pubs:1147466
Deposit date:
2020-12-01

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