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Journal article

AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation

Abstract:
Our findings establish AF10 as a novel barrier to reprogramming by regulating H3K79 methylation and thereby sheds light on the mechanism by which cell identity is maintained in somatic cells.
Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0002-9970-4870
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Role:
Author
ORCID:
0000-0003-1887-3603
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Role:
Author
ORCID:
0000-0002-2594-2956
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Role:
Author
ORCID:
0000-0001-7623-8662


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Funder identifier:
10.13039/501100000341
Grant:
20522
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Funder identifier:
10.13039/501100003043
Grant:
Installation Grant
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Funder identifier:
10.13039/100010897
Grant:
Advanced Fellowship
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Funder identifier:
10.13039/100011264
Grant:
609305


Publisher:
BioMed Central
Journal:
Epigenetics & Chromatin More from this journal
Volume:
14
Issue:
1
Pages:
32-32
Article number:
32
Publication date:
2021-07-02
DOI:
EISSN:
1756-8935
ISSN:
1756-8935


Language:
English
Keywords:
Pubs id:
1184942
Local pid:
pubs:1184942
Source identifiers:
W3176781028
Deposit date:
2026-03-25
ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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