Journal article

Efficacy of liposomal bupivacaine and bupivacaine hydrochloride vs bupivacaine hydrochloride alone as a periarticular anesthetic for patients undergoing knee replacement

Alternative title:: A randomized clinical trial

Abstract:: Importance: More than half of patients who undergo knee replacement surgery report substantial acute postoperative pain.

Objective: To evaluate the efficacy and cost-effectiveness of periarticular liposomal bupivacaine for recovery and pain management after knee replacement.

Design, Setting, and Participants: This multicenter, patient-blinded, pragmatic, randomized clinical superiority trial involved 533 participants at 11 ...
Expand abstract
Collapse abstract

Publication status:: Published

Peer review status:: Peer reviewed

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Hamilton, T., Knight, R., Stokes, J., Rombach, I., Cooper, C., Davies, L., Dutton, S., Barker, K., Cook, J., Lamb, S., Murray, D., Poulton, L., Wang, A., Strickland, L., Van Duren, B., Leal, J., Beard, D., & Pandit, H. (2022). Efficacy of liposomal bupivacaine and bupivacaine hydrochloride vs bupivacaine hydrochloride alone as a periarticular anesthetic for patients undergoing knee replacement. JAMA Surgery, 157(6), 481–489.

MLA Style

Hamilton, T., et al. “Efficacy of Liposomal Bupivacaine and Bupivacaine Hydrochloride vs Bupivacaine Hydrochloride Alone as a Periarticular Anesthetic for Patients Undergoing Knee Replacement.” JAMA Surgery, vol. 157, no. 6, American Medical Association, 2022, pp. 481–89.

Chicago Style

Hamilton, T, R Knight, J Stokes, I Rombach, C Cooper, L Davies, S Dutton, et al. 2022. “Efficacy of Liposomal Bupivacaine and Bupivacaine Hydrochloride vs Bupivacaine Hydrochloride Alone as a Periarticular Anesthetic for Patients Undergoing Knee Replacement.” JAMA Surgery 157 (6): 481–89.
Share
Print

Access Document

Files:: Hamilton_et_al_2022_efficacy_of_liposomal.pdf

(Preview, Version of record, pdf, 339.0KB, Terms of use)

Publisher copy:: 10.1001/jamasurg.2022.0713

Authors

+ Hamilton, T More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDORMS
Role:: Author

+ Knight, R More by this author

Role:: Author

+ Stokes, J More by this author

Role:: Author

+ Rombach, I More by this author

Role:: Author

+ Cooper, C More by this author

Role:: Author

More authors...

Contributors

+ Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK) Study Group

Role:: Contributor

+ National Institute for Health Research More from this funder

Publisher:: American Medical Association
Journal:: JAMA Surgery More from this journal
Volume:: 157
Issue:: 6
Pages:: 481-489
Publication date:: 2022-04-06
Acceptance date:: 2022-01-11
DOI:: 10.1001/jamasurg.2022.0713
EISSN:: 2168-6262
ISSN:: 2168-6254

Language:: English
Keywords:: FFR
Pubs id:: 1231812
Local pid:: pubs:1231812
Deposit date:: 2022-01-12

Terms of use

Copyright holder:: Hamilton et al
Copyright date:: 2022
Rights statement:: © 2022 Hamilton TW et al. JAMA Surgery. This is an open access article distributed under the terms of the CC-BY License.

Licence:: CC Attribution (CC BY)

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP