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Plasmodium falciparum: the human agglutinating antibody response to the infected red cell surface is predominantly variant specific.

Abstract:

There is mounting evidence that an important component of the host-protective immune response to Plasmodium falciparum is the antibody response to the altered surface of the infected erythrocyte. The nature of these surface changes and the responses to them have been difficult to analyse because of the diverse nature of the parasite-derived neoantigens (PDN) expressed, because of the additional presence of modified host determinants, and because of the lack of monospecific reagents. We have s...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Journal:
Experimental parasitology
Volume:
75
Issue:
3
Pages:
281-292
Publication date:
1992-11-05
DOI:
EISSN:
1090-2449
ISSN:
0014-4894
URN:
uuid:54fde73e-1feb-452a-a415-540b07c8b765
Source identifiers:
11917
Local pid:
pubs:11917

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