- Abstract:
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Background Sacubitril/valsartan reduces the risk of cardiovascular mortality among patients with heart failure with reduced ejection fraction, but its effects on kidney function and cardiac biomarkers in people with moderate-to-severe chronic kidney disease are unknown. Methods UK HARP-III was a randomised double-blind trial which included 414 participants with an estimated glomerular filtration rate (GFR) 20-60 mL/min/1.73m2 who were randomly assigned to s... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 255.6KB)
-
- Publisher copy:
- 10.1161/CIRCULATIONAHA.118.034818
-
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- Publisher:
- American Heart Association Publisher's website
- Journal:
- Circulation Journal website
- Volume:
- 138
- Issue:
- 15
- Pages:
- 1505-1514
- Publication date:
- 2018-10-08
- Acceptance date:
- 2018-06-22
- DOI:
- EISSN:
-
1524-4539
- ISSN:
-
0009-7322
- URN:
-
uri:54dfd3de-2813-4b3c-870d-103d3c465841
- UUID:
-
uuid:54dfd3de-2813-4b3c-870d-103d3c465841
- Local pid:
- pubs:905648
- Copyright holder:
- Haynes et al.
- Copyright date:
- 2018
- Notes:
- © 2018 The Authors. Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited and is not used for commercial purposes.
Journal article
Effects of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: a randomised double-blind trial
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