Journal article
Developing a single-molecule fluorescence tool to quantify DNA damage
- Abstract:
- Quantification of DNA damage is an important technique for medical physics, for example to assess damage caused by the quinolone antibiotics, or to examine the effects of novel cancer treatments such as low-temperature plasma therapy on healthy or tumorous cells. Existing damage quantification techniques such as the alkaline comet assay [1] are often subjective in their results, especially at higher damage levels. Methods using immunofluorescence [2] often lose information due to the three dimensional nature of the cell.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 64.9KB, Terms of use)
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- Publisher copy:
- 10.1016/j.bpj.2015.11.914
- Publisher:
- Elsevier
- Journal:
- Biophysical Journal More from this journal
- Volume:
- 110
- Issue:
- 3 suppl. 1
- Pages:
- p164a
- Publication date:
- 2016-02-28
- DOI:
- EISSN:
-
1542-0086
- ISSN:
-
0006-3495
- Keywords:
- Pubs id:
-
pubs:638074
- UUID:
-
uuid:54846e4c-77aa-4069-b86e-79402ad97962
- Local pid:
-
pubs:638074
- Source identifiers:
-
638074
- Deposit date:
-
2016-08-09
Terms of use
- Copyright holder:
- Helen Miller et al
- Copyright date:
- 2016
- Notes:
-
This is the
accepted manuscript of a journal article published by Elsevier in Biophysical Journal on 2016-02-28, available online: http://dx.doi.org/10.1016/j.bpj.2015.11.914
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