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Natural products as a source for novel antibiotics

Abstract:

Natural products have historically been of crucial importance in the identification and development of antibacterial agents. Interest in these systems has waned in recent years, but the rapid emergence of resistant bacterial strains has forced their re-evaluation as a route to identify novel chemical skeletons with antibacterial activity for elaboration in drug development. This overview examines the current situation, highlights new natural product systems which have been found, together wit...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.tips.2016.05.001

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Trends in Pharmacological Sciences Journal website
Volume:
37
Issue:
8
Pages:
689-701
Publication date:
2016-06-04
Acceptance date:
2016-05-02
DOI:
EISSN:
1873-3735
ISSN:
0165-6147
Source identifiers:
629333
Language:
English
Keywords:
Pubs id:
pubs:629333
UUID:
uuid:53d851f3-3719-4ac3-aa5a-b70ac82e4115
Local pid:
pubs:629333
Deposit date:
2016-07-10

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