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Conserved domains of the class A scavenger receptors: evolution and function.

Abstract:

The class A scavenger receptors are phagocytic pattern recognition receptors that are well represented in vertebrate genomes. The high level of conservation among vertebrates implies that this is an evolutionarily conserved family of receptors and indicates the presence of a common ancestral gene. The identity of this ancestral gene is not clear, as it appears that many of the domains of the scavenger receptors (e.g. collagenous, scavenger receptor cysteine rich) originated early in evolution...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Immunological reviews
Volume:
227
Issue:
1
Pages:
19-31
Publication date:
2009-01-05
DOI:
EISSN:
1600-065X
ISSN:
0105-2896
URN:
uuid:5391f3a6-6cdc-4ff0-88fd-ad227b985e20
Source identifiers:
7061
Local pid:
pubs:7061

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