Journal article
Improved oxidation of aromatic and aliphatic hydrocarbons using rate enhancing variants of P450Bm3 in combination with decoy molecules
- Abstract:
- Enzyme performance can be improved using decoy molecules or engineered variants to accelerate the activity without affecting selectivity. Here we combine a rate accelerator variant of cytochrome P450Bm3 with decoy molecules to enhance the oxidation activity of a range of small organic molecules. This combined approach offers superior biocatalytic efficiency without modifying the product distribution.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 1.3MB, Terms of use)
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- Publisher copy:
- 10.1039/c5cc09247g
Authors
- Publisher:
- Royal Society of Chemistry
- Journal:
- Chemical Communications More from this journal
- Volume:
- 52
- Issue:
- 5
- Pages:
- 1036-1039
- Publication date:
- 2015-11-17
- Acceptance date:
- 2015-11-17
- DOI:
- EISSN:
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1364-548X
- ISSN:
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1359-7345
- Pmid:
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26593228
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:588847
- UUID:
-
uuid:531bf248-2b36-4dd8-a6ea-353fe461ee06
- Local pid:
-
pubs:588847
- Source identifiers:
-
588847
- Deposit date:
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2019-05-19
- ARK identifier:
Terms of use
- Copyright holder:
- Munday et al
- Copyright date:
- 2015
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from The Royal Society of Chemistry at: https://doi.org/10.1039/c5cc09247g
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