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A preclinical setup for spatially fractionated radiation therapy with electrons

Abstract:

Background: Spatially fractionated radiation therapy (SFRT) has therapeutic potential as a priming therapy which boosts tumor control. However, the optimal delivery and spatial fractionation parameters have not been deciphered and the mechanisms at play are not yet fully understood. Purpose: This paper highlights our preclinical setups for mini‐grid SFRT with 6 MeV electrons delivered at conventional to ultrahigh dose rates, using a flexible collimator system. These setups let us explore rele...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/mp.70448

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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
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Author
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author


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Funder identifier:
https://ror.org/03x94j517
Grant:
MR/X006611/1


Publisher:
Wiley
Journal:
Medical Physics More from this journal
Volume:
53
Issue:
5
Article number:
e70448
Publication date:
2026-04-24
Acceptance date:
2026-04-07
DOI:
EISSN:
2473-4209
ISSN:
0094-2405


Language:
English
Keywords:
Source identifiers:
3981514
Deposit date:
2026-04-24
ARK identifier:
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