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Sex-specific cardiometabolic multimorbidity, metabolic syndrome and left ventricular function in heart failure with preserved ejection fraction in the UK Biobank

Abstract:

Background: Cardiometabolic disturbances play a central role in the pathogenesis of heart failure with preserved ejection fraction (HFpEF). Due to its complexity, HFpEF is a challenging condition to treat, making phenotype-specific disease management a promising approach. However, HFpEF phenotypes are heterogenous and there is a lack of detailed evidence on the different, sex-specific profiles of cardiometabolic multimorbidity and metabolic syndrome present in HFpEF. Methods: We performed a r...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12933-025-02788-4

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Sub department:
Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Sub department:
Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Radcliffe Department of Medicine
Role:
Author


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Funder identifier:
https://ror.org/029chgv08
More from this funder
Funder identifier:
https://ror.org/02wdwnk04


Publisher:
BioMed Central
Journal:
Cardiovascular Diabetology More from this journal
Volume:
24
Issue:
1
Article number:
238
Publication date:
2025-06-04
Acceptance date:
2025-05-13
DOI:
EISSN:
1475-2840


Language:
English
Keywords:
Pubs id:
2128318
Local pid:
pubs:2128318
Source identifiers:
3003212
Deposit date:
2025-06-05
ARK identifier:
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