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Journal article

Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17.

Abstract:

Coronary artery disease (CAD) is a leading cause of death world-wide, and most cases have a complex, multifactorial aetiology that includes a substantial heritable component. Identification of new genes involved in CAD may inform pathogenesis and provide new therapeutic targets. The PROCARDIS study recruited 2,658 affected sibling pairs (ASPs) with onset of CAD before age 66 y from four European countries to map susceptibility loci for CAD. ASPs were defined as having CAD phenotype if both ha...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
PLoS genetics
Volume:
2
Issue:
5
Pages:
e72
Publication date:
2006-05-01
DOI:
EISSN:
1553-7404
ISSN:
1553-7390
Source identifiers:
49242
Language:
English
Keywords:
Pubs id:
pubs:49242
UUID:
uuid:52c765ec-863c-479d-b428-b0b6417ed96e
Local pid:
pubs:49242
Deposit date:
2012-12-19

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