- Abstract:
-
High-quality monoclonal antibodies (mAbs) with specificity for relevant disease molecules can now be produced in abundance. Anti-tumour necrosis factor-alpha therapies have set a new standard for symptom control in rheumatoid arthritis, and blockade of tumour necrosis factor has the potential to protect joints from structural damage. Other targets for therapeutic antibodies include the cytokines interleukin (IL)-1, IL-6, IL-8, IL-15, IL-17 and IL-18. In addition, there is preliminary evidence...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s1471-4892(03)00032-8
-
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- Journal:
- Current opinion in pharmacology
- Volume:
- 3
- Issue:
- 3
- Pages:
- 323-328
- Publication date:
- 2003-06-05
- DOI:
- EISSN:
-
1471-4973
- ISSN:
-
1471-4892
- URN:
-
uuid:5285acb2-db50-4730-924c-56ebbc331d7d
- Source identifiers:
-
227095
- Local pid:
- pubs:227095
- Language:
- English
- Keywords:
- Copyright date:
- 2003
Journal article
Antibody therapy for rheumatoid arthritis.
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