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Journal article

Interaction of viral capsid-derived virus-like particles (VLPs) with the innate immune system

Abstract:
Virus-like particles (VLPs) derived from viral nucleocapsids are an important class of nanoparticles. The structure, uniformity, stability, and function of these VLPs have attracted scientists in utilizing them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. This review discusses the interaction of viral capsid-derived VLPs with the innate immune system.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/vaccines6030037

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Experimental Medicine
Role:
Author
ORCID:
0000-0003-3510-9148
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Oxford college:
Christ Church
Role:
Author


Publisher:
MDPIAG
Journal:
Vaccines More from this journal
Volume:
6
Issue:
3
Publication date:
2018-07-02
Acceptance date:
2018-06-28
DOI:
EISSN:
2076-393X
Pmid:
30004398


Language:
English
Keywords:
Pubs id:
pubs:891169
UUID:
uuid:527f01fa-39a0-4538-a535-bf15ce53ca4b
Local pid:
pubs:891169
Source identifiers:
891169
Deposit date:
2018-07-30

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