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Sleep disorders in early psychosis: Incidence, severity, and association with clinical symptoms

Abstract:
Sleep disturbance is known to be associated with psychosis, but sleep disorders (eg, insomnia, nightmare disorder, sleep apnea) have rarely been investigated. We aimed to provide the first detailed assessment of sleep disorders and their correlates in patients with early psychosis. Sixty outpatients aged between 18 and 30 with nonaffective psychosis were assessed for sleep disorder presence, severity, and treatment using a structured diagnostic interview, sleep diaries, and actigraphy. Psychotic experiences, mood, and psychological wellbeing were also measured. Forty-eight patients (80%) had at least one sleep disorder, with insomnia and nightmare disorder being the most common. Comorbidity of sleep disorders within this group was high, with an average of 3.3 sleep disorders per patient. Over half of the sleep disorders had been discussed with a clinician but almost three-quarters had received no treatment. Treatment according to clinical guidelines was rare, occurring in only 8% of cases (n = 13). Sleep disorders were significantly associated with increased psychotic experiences, depression, anxiety, fatigue, and lower quality of life. Sleep disorders are very common in patients with psychosis, may have wide-ranging negative effects, and merit routine assessment and treatment in psychiatric practice.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/schbul/sby129

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Oxford college:
Balliol College
Role:
Author
ORCID:
0000-0002-9374-0950
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Role:
Author


More from this funder
Funding agency for:
Freeman, D
Grant:
Professorship (grant number RP-2014-05-003
Oxford Health Biomedical Research Centre
More from this funder
Funding agency for:
Sheaves, B
Freeman, D
Grant:
Strategic Award (098461/Z/12/Z
Professorship (grant number RP-2014-05-003
More from this funder
Funding agency for:
Reeve, S
Grant:
Balliol College Dervorguilla Scholarship
More from this funder
Funding agency for:
Reeve, S
Grant:
Balliol College Dervorguilla Scholarship


Publisher:
Oxford University Press
Journal:
Schizophrenia Bulletin More from this journal
Volume:
45
Issue:
2
Pages:
287–295
Publication date:
2017-01-02
Acceptance date:
2016-12-19
DOI:
EISSN:
1745-1701
ISSN:
0586-7614
Pmid:
30202909


Language:
English
Keywords:
Pubs id:
pubs:919043
UUID:
uuid:5215a295-c17f-4041-b9c6-52c12529df5f
Local pid:
pubs:919043
Source identifiers:
919043
Deposit date:
2018-10-05

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