New insights into the biological basis of genomic disorders.

Journal article

Many clinical syndromes result from deletion or duplication of regions within the human genome. Two new studies demonstrate strong connections between such events and allelic recombination in humans, which in the future may enable researchers to better predict the locations of unstable genomic regions.

Authors: Myers, S; McCarroll, SA

• Publication status: Published
• Journal: Nature genetics
• Volume: 38
• Issue: 12
• Pages: 1363-1364
• Publication date: 2006-12-01
• DOI: 10.1038/ng1206-1363
• EISSN: 1546-1718
• ISSN: 1061-4036
• Language: English
• Keywords: Meiosis; Male; Recombination, Genetic; Female; Repetitive Sequences, Nucleic Acid; Alleles; Genetic Diseases, Inborn; Syndrome; Gene Deletion; Gene Duplication; Humans