Journal article icon

Journal article

Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment

Abstract:

A significant proportion of children have unexplained problems acquiring proficient linguistic skills despite adequate intelligence and opportunity. Developmental language disorders are highly heritable with substantial societal impact. Molecular studies have begun to identify candidate loci, but much of the underlying genetic architecture remains undetermined. We performed whole-exome sequencing of 43 unrelated probands affected by severe specific language impairment, followed by independent...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

Actions


Access Document


Files:
Publisher copy:
10.1038/srep46105

Authors


Reader, RH More by this author
Hoischen, A More by this author
Veltman, JA More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Experimental Psychology
Expand authors...
Max Planck Society More from this funder
Publisher:
Nature Research Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Pages:
Article: 46105
Publication date:
2017-04-25
Acceptance date:
2017-03-08
DOI:
EISSN:
2045-2322
Pubs id:
pubs:692244
URN:
uri:518c8ba0-aec3-460d-acfd-60e802ee7a59
UUID:
uuid:518c8ba0-aec3-460d-acfd-60e802ee7a59
Local pid:
pubs:692244

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP