Improving animal phylogenies with genomic data.

Journal article

Since the first animal genomes were completely sequenced ten years ago, evolutionary biologists have attempted to use the encoded information to reconstruct different aspects of the earliest stages of animal evolution. One of the most important uses of genome sequences is to understand relationships between animal phyla. Despite the wealth of data available, ranging from primary sequence data to gene and genome structures, our lack of understanding of the modes of evolution of genomic characters means that using these data is fraught with potential difficulties, leading to errors in phylogeny reconstruction. Improved understanding of how different character types evolve, the use of this knowledge to develop more accurate models of evolution, and denser taxonomic sampling, are now minimizing the sources of error. The wealth of genomic data now being produced promises that a well-resolved tree of the animal phyla will be available in the near future.

Authors: Telford, M; Copley, R

• Publication status: Published
• Journal: Trends in genetics : TIG
• Volume: 27
• Issue: 5
• Pages: 186-195
• Publication date: 2011-05-01
• DOI: 10.1016/j.tig.2011.02.003
• ISSN: 0168-9525
• Language: English
• Keywords: Animals; Models, Genetic; Humans; Genome; Phylogeny; Gene Expression Profiling; Evolution, Molecular