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Mass-selective soft-landing of protein assemblies with controlled landing energies.

Abstract:

Selection and soft-landing of bionanoparticles in vacuum is potentially a preparative approach to separate heterogeneous mixtures for high-resolution structural study or to deposit homogeneous materials for nanotechnological applications. Soft-landing of intact protein assemblies however remains challenging, due to the difficulties of manipulating these heavy species in mass-selective devices and retaining their structure during the experiment. We have developed a tandem mass spectrometer wit...

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Publication status:
Published

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Publisher copy:
10.1021/ac5018327
Publisher:
American Chemical Society
Journal:
Analytical chemistry More from this journal
Volume:
86
Issue:
16
Pages:
8321-8328
Publication date:
2014-08-01
DOI:
EISSN:
1520-6882
ISSN:
0003-2700
Language:
English
Pubs id:
pubs:475904
UUID:
uuid:517a12aa-96f6-4a1e-9510-431371a04c2a
Local pid:
pubs:475904
Source identifiers:
475904
Deposit date:
2014-08-15

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