- Abstract:
-
We have identified a gene for the addition of N-acetylneuraminic acid (Neu5Ac) in an alpha-2,3-linkage to a lactosyl acceptor moiety of the lipopolysaccharide (LPS) of the human pathogen Haemophilus influenzae. The gene is one that was identified previously as a phase-variable gene known as lic3A. Extracts of H. influenzae, as well as recombinant Escherichia coli strains producing Lic3A, demonstrate sialyltransferase activity in assays using synthetic fluorescent acceptors with a terminal gal...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1046/j.1365-2958.2001.02204.x
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- Journal:
- Molecular microbiology
- Volume:
- 39
- Issue:
- 2
- Pages:
- 341-350
- Publication date:
- 2001-01-05
- DOI:
- EISSN:
-
1365-2958
- ISSN:
-
0950-382X
- URN:
-
uuid:51603023-d12a-46fb-a099-0a52ff3b90e9
- Source identifiers:
-
115623
- Local pid:
- pubs:115623
- Copyright date:
- 2001
Journal article
Identification of a lipopolysaccharide alpha-2,3-sialyltransferase from Haemophilus influenzae.
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