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Quinidine in falciparum malaria.

Abstract:

Fourteen patients with falciparum malaria were successfully treated with oral quinidine. Twelve of these patients were followed for 35 days without recrudescence. In six patients the infection had already recrudesced after antimalarial treatment, which in two cases had included a full course of quinine. Quinidine caused no cardiotoxicity, although the electrocardiogram QTc interval was prolonged by more than 25% in four patients. In-vitro cultures from nine of these patients and a further sev...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Looareesuwan, S More by this author
Warrell, DA More by this author
Chongsuphajaisiddhi, T More by this author
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Journal:
Lancet
Volume:
2
Issue:
8255
Pages:
1069-1071
Publication date:
1981-11-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:5098b019-883c-4e42-b524-0c3cd3a7b787
Source identifiers:
41967
Local pid:
pubs:41967

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