Journal article

On negative heritability and negative estimates of heritability

Abstract:: We consider the problem of interpreting negative maximum likelihood estimates of heritability that sometimes arise from popular statistical models of additive genetic variation. These may result from random noise acting on estimates of genuinely positive heritability, but we argue that they may also arise from misspecification of the standard additive mechanism that is supposed to justify the statistical procedure. Researchers should be open to the possibility that negative heritability estimates could reflect a real physical feature of the biological process from which the data were sampled.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Steinsaltz, D., Dahl, A., & Wachter, K. W. (2020). On negative heritability and negative estimates of heritability. Genetics, 214(4), genetics.303161.2020.

MLA Style

Steinsaltz, D, et al. “On Negative Heritability and Negative Estimates of Heritability.” Genetics, vol. 214, no. 4, 2020, p. genetics.303161.2020.

Chicago Style

Steinsaltz, D, A Dahl, and KW Wachter. 2020. “On Negative Heritability and Negative Estimates of Heritability.” Genetics 214 (4): genetics.303161.2020.
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Publisher copy:: 10.1534/genetics.120.303161

Authors

+ Steinsaltz, D More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Statistics
Sub department:: Statistics
Role:: Author

+ Dahl, A More by this author

Role:: Author

+ Wachter, KW More by this author

Role:: Author

Publisher:: Genetics Society of America
Journal:: Genetics More from this journal
Volume:: 214
Issue:: 4
Pages:: genetics.303161.2020
Publication date:: 2020-04-14
Acceptance date:: 2020-03-30
DOI:: 10.1534/genetics.120.303161
EISSN:: 1943-2631
ISSN:: 0016-6731

Language:: English
Keywords:: FFR
Pubs id:: 1101071
Local pid:: pubs:1101071
Deposit date:: 2020-04-23
ARK identifier:: ark:/29072/ora_50266466b0ef4d8bab5479ab561b5e81

Terms of use

Copyright holder:: Genetics
Copyright date:: 2020
Rights statement:: © 2020, Genetics

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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