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Application of ultrafiltration to improve the extraction of antibiotics

Abstract:

The production of antibiotics typically consists of fermentation, removal of biomass, solvent extraction, and crystallization. Vacuum rotary filtration or other conventional filtration systems and microfiltration are used to remove the biomass, but the biomass removal step fails to remove macromolecules including polysaccharides and proteins which may act as emulsifiers causing emulsion in the subsequent solvent extraction process, and reducing the process efficiency and product quality. In t...

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Publication status:
Published

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Volume:
34
Issue:
1-3
Pages:
115-123
Publication date:
2004-01-01
DOI:
ISSN:
1383-5866
URN:
uuid:4fd90477-cafc-4dad-b454-d68c33f6688e
Source identifiers:
61935
Local pid:
pubs:61935

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