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Reinforcement signalling in Drosophila; dopamine does it all after all

Abstract:

Reinforcement systems are believed to drive synaptic plasticity within neural circuits that store memories. Recent evidence from the fruit fly suggests that anatomically distinct dopaminergic neurons ultimately provide the key instructive signals for both appetitive and aversive learning. This dual role for dopamine overturns the previous model that octopamine signalled reward and dopamine punishment. More importantly, this anatomically segregated double role for dopamine in reward and aversi...

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Publisher copy:
10.1016/j.conb.2013.01.005

Authors


Waddell, S More by this author
Journal:
Current Opinion in Neurobiology
Volume:
23
Issue:
3
Pages:
324-329
Publication date:
2013-06-05
DOI:
EISSN:
1873-6882
ISSN:
0959-4388
URN:
uuid:4fcfa3ac-4ae1-4f01-90ec-1d4aeb29443c
Source identifiers:
406475
Local pid:
pubs:406475
Language:
English

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